Unintentional drug overdose is a leading cause of preventable death in the United States. Administering naloxone hydrochloride (“naloxone”) can reverse an opioid overdose and prevent unintentional death. Since 2001, states have enacted naloxone laws to increase access, simplify prescribing and dispensing by health care providers, and encourage its use by individuals in a position to assist a person experiencing a drug overdose.